CIMETIDINE: Tab./Syrup/injection
Ind: Peptic ulceration, recurrent and stomal ulceration, Zollinger-Ellison syndrome; Reflux oesophagitis and other conditions where a reductation of gastric acid is beneficial, erosive gastritis with bleeding.
Cautions: Impaired renal functions (reduce dosage), exclude malignant disease, as cimetidine may mask symptoms and delay treatment; long-term treatment should be avoided (if possible) otherwise the patient should be kept under observation or monitored; avoid abrupt withdrawal of treatment, concurrent admin. of anticoagulants or phenytoin.
S/E: Occasional diarrhoea, dizziness, rashes, rarely mental confusion, and gynecomastia.
Dose: Adult- by mouth, duodenal & benign gastric ulcer, 400mg, 2 times daily with breakfast & at bedtime or 800 mg at bedtime for a minimum 4 weeks, then 400mg. once or twice daily as a maintenance dose. Reflux oesophagitis- 400mg 4 times a day after meals.
By injection- 200mg i.m. or slow i.v.( 100-150mg/hour) 4 to 6 hourly, max. dose 2 gm. daily.
Child- not recommended.
*G-CIMETIDINE Inj. Gonoshastho.
Cimetidine 200mg/2ml ampoule: injection 25 amps pack: 107.25 MRP