RANITIDINE: Tablet/Syrup/Injection
Ind: Duodenal, benign gastric and postoperative ulceration, reflux oesophagitis, Zollinger- Ellison syndrome, and other conditions where a reduction of gastric acid is beneficial.
S/E: No serious adverse effects have been reported to date. But rare and transient nausea, headache, dizziness, and diarrhoea may occur. Anaphylactoid reactions & skin rashes have been reported rarely.
Caution: Caution should be taken in case of renal impairment, pregnancy, lactation; exclude malignantly diseases before treatment. Carry out periodic examinations of patients on prolonged therapy
Dose: Adult- benign gastric and duodenal ulcer, 150mg (1 tab or 2 ts) b.id. in the morning and at bedtime; or 300mg at bedtime for 4 weeks; maintenance therapy, at bedtime.
Reflux oesophagitis, 150mg b.i.d.for up to 8 weeks. Zollinger-Ellison syndrome, the starting dose is 150 mg t.d.s. and maybe increased as necessary to 900mg (six tablets).
Child- Under 8 yrs. not recommended; over 8 yrs. up to 150mg twice daily. By injection: adult- 50mg. 1.m. or by slow IV. Inj. or infusion, repeated 6 to 8 hourly.
Child- not recommended.