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Tolperisone Hydrochloride: Uses,Dosage,Side Effects

Generic Name
Tolperisone Hydrochloride
Therapeutic Class:
Central Depolarizing muscle relaxants, Centrally acting Skeletal Muscle Relaxants

Indications:
Increased tone of skeletal muscles due to organic neurological disorders (e.g. injury of the pyramidal tract, multiple sclerosis, myelopathy, encephalomyelitis, etc.), muscular hypertension, muscular spasm, muscular contracture, rigidity, spinal automatism, and discopathy. Obliterative vascular diseases (obliterative arteriosclerosis, diabetic angiopathy, obliterative thromboangitis, Raynaud\'s disease, diffuse scleroderma) and disorders due to injured innervation of the vessels (acrocyanosis, intermittent angioneurotic dysbasia). In individual cases post-thrombotic venous and lymphatic circulation disorders, crural ulcer.

Presentation:
Tolperisone 50: Each film-coated tablet contains Tolperisone Hydrochloride INN 50 mg.
Tolperisone 100: Each film-coated tablet contains Tolperisone Hydrochloride INN 100 mg.

Description:
Tolperisone Hydrochloride is a centrally acting muscle relaxant. It effectively reduces muscular hypertonicity, improves peripheral blood flow by vasodilatation, and reduces pain.

Dosage & Administration:
One should follow the doctor\'s instructions regarding the dosage of Tolperisone. The recommended dose is as follows:
Tablet
Adult: 50-150 mg three times daily according to the individual requirement and tolerance of the patient.
Children (from 3 months to 6 years): 5-10 mg/kg/day in three divided doses.
Children (from 6 to 14 years): 2-4 mg/kg/day in three divided doses.

Side Effects:
Sometimes, muscular weakness, headache, nausea, vomiting, and rarely hypersensitivity reactions may occur as side effects

Precautions:
In the case of children, the prescribed dose and duration of treatment should closely be observed

Use in Pregnancy & Lactation:
Tolperisone hydrochloride should be used in pregnancy according to physician\'s advice. Tolperisone hydrochloride should not be used during breast-feeding

Interaction:
Concomitant use of methocarbamol with tolperisone hydrochloride has been reported to cause disturbance of visual accommodation.

Overdose:
In the event of overdosage supportive therapy may be substituted.

Storage:
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.

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