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Triamcinolone Acetonide: Uses,Dosage,Side Effects

Generic Name
Triamcinolone Acetonide
Therapeutic Class:
Respiratory (Corticosteroid, Glucocorticoids, Nasal Steroid Preparations)

Indications:
Triamcinolone AcetonideNasal Spray is indicated for the treatment of the nasal symptoms of seasonal and perennial allergic rhinitis in adults and children 2 years of age and older.

Presentation:
Triamcinolone Acetonide Nasal Spray: Each bottle contains 120 metered doses of Triamcinolone Acetonide. Each actuation delivers Triamcinolone Acetonide BP 55 mcg.

Description:
Triamcinolone Acetonide is a corticosteroid. It is a more potent derivative of Triamcinolone and approximately 8 times more potent than Prednisone. Although the precise mechanism of corticosteroid antiallergic action is unknown, corticosteroids are very effective.

Dosage & Administration:
Adults and children 12 years of age and older: The recommended starting and maximum dose is 220 mcg per day as two sprays in each nostril once daily.
Children 2 to 12 years of age: The recommended starting dose is 110 mcg per day given as one spray in each nostril once daily. The maximum recommended dose is 220 mcg per day as two sprays per nostril once daily.

Side Effects:
Generally, Triamcinolone Acetonide is well tolerated. However, few side effects such as-pharyngitis, epistaxis, increase in cough, headache, infection, sinusitis, and vomiting may occur.

Precautions:
Triamcinolone Acetonide nasal spray should be used with caution, if at all, in patients with active or quiescent tuberculous infection of the respiratory tract or in patients with untreated fungal, bacterial, or systemic viral infections or ocular herpes simplex. In clinical studies with Triamcinolone Acetonide nasal spray, the development of localized infections of the nose and pharynx with Candida albicans has rarely occurred.

Use in Pregnancy & Lactation:
Pregnancy: There are no adequate and well-controlled studies in pregnant women. Triamcinolone Acetonide nasal spray, like other corticosteroids, should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Lactation: It is not known whether Triamcinolone Acetonide is excreted in human milk. Because other corticosteroids are excreted in human milk, caution should be exercised when Triamcinolone Acetonide nasal spray is administered to nursing women.

Overdose:
Like any other nasally administered corticosteroids, acute overdosing is unlikely in view of the total amount of active ingredient present. In the event that the entire contents of the bottle were administered all at once, via either oral or nasal application, clinically significant systemic adverse events would most likely not result. The patient may experience some gastrointestinal upset.

Storage:
Store at a temperature not exceeding 25˚C. Protect from light and moisture. Keep out of the reach of children.

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