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Mebhydrolin Napadisylate: Uses,Dosage,Side Effects

Generic Name
Mebhydrolin Napadisylate
Therapeutic Class: Sedating Antihistamine

Indications:
Mebhydrolin Napadisylate is indicated in-
  • Allergic disease or symptoms such as urticaria
  • Pruritus of various origin
  • Eczema
  • Itching
  • Drug rash
  • Insect bites
  • Allergic conjunctivitis
  • Dermatitis of nutritional origin
  • Hay fever,
  • Vasomotor rhinitis
  • Allergic asthma.
Presentation:
Each tablet contains Mebhydrolin Napadisylate INN 76 mg equivalent to Mebhydrolin 50 mg.

Description:
Mebhydrolin diminishes or abolishes the main actions of histamine in the body by blocking of histamine receptors.

Dosage & Administration:
  • Adults and children over 10 years: 2-6 tablets daily
  • Children 5-10 years: 2-4 tablets daily
  • Children 2-5 years: 1-3 tablets daily
  • Children upto 2 years: 1-2 tablets daily
Treatment should be given in several single doses daily. Mebhydrolin may be swallowed during or shortly after meals. For children, the tablet may be crushed and mixed with food.

Interaction:
The effects of atropine and tricyclic anti-depressants may be enhanced by Mebhydrolin. It may mask the warning symptoms of damage caused by ototoxic drugs.

Contraindications:
Hypersensitivity to any of the ingredients of Mebhydrolin tablet or to mebhydrolin
Prostatic hypertrophy, narrow-angle glaucoma.
First trimester of pregnancy.

Side Effects:
Lassitude, dizziness, hypotension, muscular weakness, nausea, vomiting, diarrhoea or constipation, epigastric pain, headache, blurred vision, tinnitus, depression, nightmares, anorexia, dryness of the mouth, tightness of the chest, tingling, sedation, drowsiness etc. may occur.

Pregnancy & Lactation:
Safety in pregnancy and lactation has not been established.

Precautions & Warnings:
The substance may cause drowsiness, if affected, driving or operating machinery & alcoholic drinks should be avoided.

Use in Special Populations:
Safety in pregnancy and lactation has not been established.

Storage:
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.

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